Multiculturalism is good for flies, too

Good Writers Need to be Good Listeners, Too

Glyphosate: Too Much of a Good Thing?

Although previously accepted as the less toxic alternative, with low impact on animals, farmers as well as consumers who are exposed to residues in food, glyphosate chemicals are now increasingly controversial as new evidence from research is emerging. We argue that specific aspects of the history, chemistry and safety of glyphosate and glyphosate-based herbicides should be thoroughly considere...

LCZ696: too good to be true?

This issue of the European Heart Journal contains a major statement by the PARADIGM-HF Investigators, who present an ‘putative placebo’ analysis for LCZ696, a new medicine that yielded a remarkable reduction in total mortality and heart failure events in patients with significant heart failure with reduced ejection fraction (HF-REF). (NB: I serve as a consultant on Novartis’s cardiovascular–met...

Too much of a good thing is wonderful: observational data for perioperative research.

MANY of our clinical decisions are based on animal models, small in vivo studies, retrospective chart reviews, or tradition. As anesthetic safety has improved over the past few decades, the infrequent events that comprise current anesthesia morbidity are difficult to analyze using traditional research tools. Intraoperative blood pressure management research exemplifies this challenge. Although ...

Too Much of a Good Thing?*

discrepancy theories generally, assumes that people are motivated to verify their identities by seeking feedback from others which is not discrepant from their own self-views (Burke 1991; Burke and Stets 1999; Higgins 1987; Higgins, Klein, and Strauman 1985; Stets and Burke 1996; Swann 1983). When the dimension of meaning that is relevant to the identity is one of evaluation, people want others...